Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
| ▸ | PRKACB | P22694 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800766 | 0.84 | DRD2 (0.46) | DRD2DRD3PRKACAPRKACGPRKACB | |
| SCHEMBL1372580 | 0.81 | DRD2 (0.46) | DRD2DRD3HTR2APRKACAPRKACG | |
| SCHEMBL11632146 | 0.81 | PRKACA (0.52) | DRD2DRD3PRKACAPRKACGPRKACB | |
| SCHEMBL28806973 | 0.81 | PRKACA (0.55) | DRD2DRD3HTR2APRKACAPRKACG | |
| SCHEMBL27948443 | 0.81 | PRKACA (0.55) | DRD2DRD3HTR2APRKACAPRKACG | |
| SCHEMBL1639063 | 0.79 | DRD2 (0.46) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL30752424 | 0.79 | DRD2 (0.46) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL2787499 | 0.79 | HTR1A (0.47) | DRD2DRD3HTR2AHTR1AHRH1 | |
| SCHEMBL1176963 | 0.79 | DRD2 (0.46) | DRD2DRD3HTR2AHTR1AHRH1 | |
| SCHEMBL10746746 | 0.79 | HTR2C (0.47) | DRD2DRD3HTR2AHTR1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336593-A1 | Compound Having Antitumor Activity And Use Thereof | INNOVSTONE THERAPEUTICS LIMITED (CN) | 2024-10-10 | — | — | US | disclosed |
| EP-4209485-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |
| CN-109666027-A | GPR40 agonist compound of a kind of amide structure and application thereof | 中国科学院上海药物研究所 | 2019-04-23 | — | — | CN | disclosed |
| CN-107793363-A | A kind of substituted aromatic amines base heteroaromatic class compound and its application as antineoplastic | 上海医药工业研究院 | 2018-03-13 | — | — | CN | disclosed |
| CN-103896937-A | 1,2-benzisothiazol-3-one-1,2,3-triazole derivatives and application thereof | UNIV TIANJIN SCIENCE & TECH | 2014-07-02 | — | — | CN | disclosed |
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0750662-A1 | BREAKAGE-RESISTANT POLYFUNCTIONAL CLEANING TABLETS WITH A LONG SHELF LIFE, PROCESS FOR PRODUCING THEM AND THEIR USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025161-A1 | BREAKAGE-RESISTANT POLYFUNCTIONAL CLEANING TABLETS WITH A LONG SHELF LIFE, PROCESS FOR PRODUCING THEM AND THEIR USE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-09-21 | — | — | WO | disclosed |
| EP-0073835-B1 | PROCESS FOR PRODUCING POLYURETHANE POLYMER | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4168151-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4153443-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4153443-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4133673-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133673-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4126442-A | O-Phosphoroamidophenylmorpholine compounds and use as herbicides | UNITED STATES BORAX & CHEMICAL CORP. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4123251-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336593-A1 | Compound Having Antitumor Activity And Use Thereof | PRMT5, PRMT1, PRMT6 | DRD2 4482/4885DRD3 4550/4885HTR2A 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.