Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 6/20 | 0.39 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797215 | 0.88 | DHCR7 (0.41) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27884364 | 0.88 | DHCR7 (0.42) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27884197 | 0.87 | PTPN1 (0.43) | PPARGPTPN1ACP1PPARAPPARD | |
| SCHEMBL27867728 | 0.87 | ACLY (0.39) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27884471 | 0.86 | ACLY (0.37) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27867758 | 0.86 | ACLY (0.38) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27867768 | 0.85 | P2RX3 (0.39) | PPARGPPARAPPARDACLYDHCR7 | |
| SCHEMBL27713685 | 0.84 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL27733709 | 0.82 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL12096922 | 0.81 | PPARG (0.66) | PPARGPPARAPPARDACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | disclosed |