Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797222 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2MTNR1AMTNR1BHCRTR1HCRTR2 | |
| SCHEMBL3405221 | 0.80 | LMNA (0.41) | SMN1; SMN2MTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL27884408 | 0.77 | PTGDR2 (0.44) | LMNAKMT2A | |
| SCHEMBL28797225 | 0.70 | COMT (0.37) | ALDH1A1 | |
| SCHEMBL3406290 | 0.67 | KDM4E (0.43) | SMN1; SMN2MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL27850219 | 0.65 | KDM4E (0.44) | SMN1; SMN2MTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL27699219 | 0.64 | ALDH1A1 (0.35) | ALDH1A1HPGDKMT2A | |
| SCHEMBL27699407 | 0.64 | ALDH1A1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL2130866 | 0.63 | MEN1 (0.51) | SMN1; SMN2RAB9ACYP3A4KMT2A | |
| SCHEMBL61299 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102648199-A | Piperidine compound and use thereof | ASTRAZENECA AB | 2012-08-22 | — | — | CN | disclosed |