Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902312 | 0.82 | TDP1 (0.44) | ALKBH5FTOHTR6SRCBRD4 | |
| SCHEMBL27885302 | 0.81 | HTR6 (0.50) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL12324917 | 0.81 | HTR6 (0.50) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL2431470 | 0.81 | HTR6 (0.50) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL12093313 | 0.81 | HTR6 (0.70) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL20762057 | 0.81 | BRD4 (0.49) | HTR6SRCAGTR1BRD4TDP1 | |
| SCHEMBL2431900 | 0.80 | HTR6 (0.49) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL597369 | 0.77 | HTR6 (0.46) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL30644289 | 0.77 | HTR6 (0.46) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL28338517 | 0.77 | GAA (0.51) | HTR6PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102816107-B | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2015-06-03 | — | — | CN | disclosed |
| CN-102816107-A | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2012-12-12 | — | — | CN | disclosed |