SCHEMBL2431470

SCHEMBL2431470

O=S(=O)(c1ccccc1)n1c2ccccc2c2cccc(Br)c21

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 11/20 0.50
SRC P12931 2/20 0.46
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
CXCL8 P10145 1/20 0.41
NOD1 Q9Y239 1/20 0.41
PSEN1 P49768 3/20 0.41
PSEN2 P49810 3/20 0.41
APH1B Q8WW43 3/20 0.41
NCSTN Q92542 3/20 0.41
APH1A Q96BI3 3/20 0.41
PSENEN Q9NZ42 3/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C1 Q04828 1/20 0.40
AGTR1 P30556 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12324917 0.81 HTR6 (0.50) HTR6SRCFABP3FABP4FABP5
SCHEMBL12093313 0.81 HTR6 (0.70) HTR6SRCFABP3FABP4FABP5
SCHEMBL30644289 0.80 HTR6 (0.46) HTR6SRCPSEN1PSEN2APH1B
SCHEMBL597369 0.80 HTR6 (0.46) HTR6SRCPSEN1PSEN2APH1B
SCHEMBL2431900 0.80 HTR6 (0.49) HTR6SRCFABP3FABP4FABP5
SCHEMBL31304851 0.79 HTR6 (0.44) HTR6SRCCXCL8NOD1AKR1C3
SCHEMBL16812952 0.77 HTR6 (0.48) HTR6SRCFABP3FABP4FABP5
SCHEMBL4859176 0.76 HTR6 (0.41) HTR6SRCCXCL8NOD1AGTR1
SCHEMBL4543865 0.76 MTNR1B (0.47) HTR6SRCPSEN1PSEN2APH1B
SCHEMBL8540570 0.75 HTR6 (0.55) HTR6SRCFABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105038764-B Based on the asymmetrical type hot activation delay aggregation induced luminescence material of diphenyl sulphone (DPS) phenoxazine structure and its synthetic method and application 中山大学 2017-09-29 CN disclosed
US-9356243-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-05-31 US disclosed
US-9356243-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-05-31 US disclosed
US-9356243-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-05-31 US disclosed
CN-102822174-B Material for organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-04 CN disclosed
CN-105038764-A Asymmetrical thermal-activation-delayed aggregation-induced emission material based on diphenyl sulfone phenoxazine, as well as synthesis method and application of material UNIV SUN YAT SEN 2015-11-11 CN disclosed
US-20140350243-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCH PATENT GMBH (DE) 2014-11-27 US disclosed
US-20140350243-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCH PATENT GMBH (DE) 2014-11-27 US disclosed
US-20140350243-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCH PATENT GMBH (DE) 2014-11-27 US disclosed
US-8835626-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-09-16 US disclosed
US-8835626-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-09-16 US disclosed
US-8835626-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2014-09-16 US disclosed
US-20130012700-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 US disclosed
US-20130012700-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 US disclosed
US-20130012700-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 US disclosed
CN-102822174-A Material for organic electroluminescent device MERCK PATENT GMBH 2012-12-12 CN disclosed
CN-102770427-A Materials for electronic devices MERCK PATENT GMBH 2012-11-07 CN disclosed
WO-2011116865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012700-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, PIEZO1 HTR6 3531/4885SRC 3469/4885FABP3 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.