Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2427444 | 0.88 | ALDH1A1 (0.54) | HTR6SRCALDH1A1PSEN1PSEN2 | |
| SCHEMBL17287209 | 0.88 | GAA (0.49) | HTR6ALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL12324914 | 0.83 | KMT2A (0.53) | HTR6SRCALDH1A1PSEN1PSEN2 | |
| SCHEMBL12324917 | 0.80 | HTR6 (0.50) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL2431470 | 0.80 | HTR6 (0.50) | HTR6SRCPSEN1PSEN2APH1B | |
| SCHEMBL12093313 | 0.80 | HTR6 (0.70) | HTR6SRCALDH1A1PSEN1PSEN2 | |
| SCHEMBL23622783 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP2C19 | |
| SCHEMBL29881765 | 0.74 | KDM4E (0.52) | ALDH1A1CYP2C19 | |
| SCHEMBL21671297 | 0.72 | L3MBTL1 (0.63) | ALDH1A1 | |
| SCHEMBL12447557 | 0.72 | L3MBTL1 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011116865-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |