SCHEMBL27885703

SCHEMBL27885703

COc1ccc(C(=O)C(CCN)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
CYP1A2 P05177 1/20 0.55
LDHA P00338 1/20 0.51
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
PARP10 Q53GL7 2/20 0.49
GSK3B P49841 1/20 0.49
PARP1 P09874 1/20 0.49
PARP2 Q9UGN5 1/20 0.49
PARP4 Q9UKK3 1/20 0.49
HTT P42858 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SLC2A1 P11166 1/20 0.48
CYP2D6 P10635 1/20 0.48
CES2 O00748 2/20 0.47
CES1 P23141 2/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SLC6A2 P23975 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290396 0.81 ALDH1A1 (0.60) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL5217775 0.78 GSK3B (0.56) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL28859493 0.77 KIF11 (0.56) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL28859464 0.76 HTT (0.50) ALDH1A1CYP1A2CA1CA2PARP10
SCHEMBL28222504 0.76 ALDH1A1 (0.62) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL3756081 0.76 ALDH1A1 (0.72) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL28883199 0.75 ALDH1A1 (0.66) ALDH1A1CYP1A2LDHACA1CA2
Hydrochloric Acid SCHEMBL28222455 0.75 ALDH1A1 (0.60) ALDH1A1CYP1A2LDHACA1CA2
SCHEMBL28859465 0.75 CA1 (0.53) ALDH1A1CYP1A2CA1CA2PARP10
SCHEMBL10708779 0.75 NAPRT (0.45) ALDH1A1CYP1A2GSK3BHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101677931-B Wrinkling-preventing and -modifying agent SHISEDO CO LTD 2013-01-02 CN disclosed