Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900351 | 0.80 | ALDH1A1 (0.51) | CYP2C19ALDH1A1PLOD2CYP2C9KMT2A | |
| SCHEMBL4424991 | 0.78 | NAPRT (0.48) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27885703 | 0.75 | ALDH1A1 (0.55) | CYP1A2CYP2D6ALDH1A1MEN1KMT2A | |
| SCHEMBL5439920 | 0.74 | GSR (0.48) | MDM2 | |
| SCHEMBL28624819 | 0.73 | NAPRT (0.52) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10592278 | 0.72 | GRM8 (0.48) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9755838 | 0.72 | GRM8 (0.48) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6007952 | 0.72 | NAPRT (0.50) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6007960 | 0.72 | NAPRT (0.50) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9164237 | 0.71 | CYP1A2 (0.42) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012167243-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR OBESITY | B & P COMPANY, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| WO-2012167243-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR OBESITY | B & P COMPANY, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-0170933-B1 | GAMMA-AMINOBUTYRIC ACID DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | KURARAY CO., LTD. (JP) | 1988-08-31 | — | — | EP | disclosed |
| US-4703061-A | MEMORY IMPEDIMENT; BRAIN METABOLISM DYSFUNCTION | KURARAY CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| EP-0170933-A1 | Gamma-aminobutyric acid derivatives, process for production thereof, and use thereof as medicaments | KURARAY CO., LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |