Ethyl Isonipecotate

Ethyl Isonipecotate

SCHEMBL27886

CCOC(=O)C1CCNCC1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
ALDH1A1 P00352 3/20 0.49
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
TSHR P16473 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
PMP22 Q01453 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Isonipecotate SCHEMBL6439825 1.00 MAPT (0.51) MAPTALDH1A1GABRPGABRDGABRA1
Ethyl Isonipecotate SCHEMBL1420351 0.98 MAPT (0.50) MAPTALDH1A1GABRPGABRDGABRA1
SCHEMBL3476143 0.93 ALDH1A1 (0.51) MAPTALDH1A1GABRPGABRDGABRA1
Ethyl Isonipecotate SCHEMBL27812954 0.91 ALDH1A1 (0.46) MAPTALDH1A1TSHR
Hydrochloric Acid SCHEMBL15970872 0.91 ALDH1A1 (0.50) MAPTALDH1A1PKM
Ethyl Isonipecotate SCHEMBL9733648 0.89 MAPT (0.48) MAPTALDH1A1TSHRPKM
SCHEMBL12994147 0.88 MAPT (0.49) MAPTALDH1A1GABRPGABRDGABRA1
SCHEMBL8224141 0.88 MAPT (0.49) MAPTALDH1A1GABRPGABRDGABRA1
SCHEMBL2235927 0.88 MAPT (0.49) MAPTALDH1A1GABRPGABRDGABRA1
Ethyl Isonipecotate SCHEMBL20300378 0.88 MAPT (0.43) MAPTALDH1A1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4706 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
CN-119968375-A Heterocyclic derivatives as Janus kinase inhibitors 奇斯药制品公司 2025-05-09 CN claimed
US-20240383854-A1 PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES HOVIONE FARMACIENCIA SA (PT) 2024-11-21 US claimed
CN-118146163-A Benzimidazole derivative and preparation method thereof 雅安职业技术学院 2024-06-07 CN claimed
US-20240150317-A1 Chemical Process for the Synthesis of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline GENZYME CORPORATION (US) 2024-05-09 US claimed
CN-117929554-A Method for measuring content of 4-ethyl piperidine formate in atorvastatin maleate and application thereof 南京明捷生物医药检测有限公司 2024-04-26 CN claimed
CN-117756779-A Synthesis method of 1- (pyridine-3-yl) piperidine-4-carboxylic acid 宁波职业技术学院 2024-03-26 CN claimed
CN-115068477-B Application of rapamycin derivatives in preparation of antitumor drugs 福建省微生物研究所 2024-02-09 CN claimed
CN-117298108-A Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof 浙江师范大学 2023-12-29 CN claimed
CN-115160343-B Rapamycin derivative, and preparation method and application thereof 福建省微生物研究所 2023-11-14 CN claimed
EP-0765865-B1 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION SEIKAGAKU KOGYO CO LTD (JP) 2001-12-12 EP claimed
WO-2001023392-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-05 WO claimed
WO-2001021634-A1 BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-03-29 WO claimed
US-5763438-A ANTIVIRAL AGENTS SEIKAGAKU CORPORATION (JP) 1998-06-09 US claimed
EP-0765865-A1 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION SEIKAGAKU CORPORATION (JP) 1997-04-02 EP claimed
US-5378691-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US claimed
EP-0188805-B1 1,3-DITHIOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-09-06 EP claimed
US-4737494-A 2-YLIDENE AMMONIUM COMPOUNDS USED IN TREATING LIVER DISEASES BANYU PHARMACEUTICAL CO., LTD. (JP) 1988-04-12 US claimed
EP-0188805-A1 1,3-Dithiole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-30 EP claimed
EP-0005232-B1 ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1982-08-25 EP claimed