Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Isonipecotate SCHEMBL27886 | 0.89 | MAPT (0.51) | MAPTPKMALDH1A1TSHR | |
| Ethyl Isonipecotate SCHEMBL6439825 | 0.89 | MAPT (0.51) | MAPTPKMALDH1A1TSHR | |
| Ethyl Isonipecotate SCHEMBL1420351 | 0.88 | MAPT (0.50) | MAPTPKMALDH1A1TSHR | |
| Ethyl Isonipecotate SCHEMBL27818566 | 0.86 | PKM (0.54) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL3476143 | 0.83 | ALDH1A1 (0.51) | MAPTPKMALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15970872 | 0.81 | ALDH1A1 (0.50) | MAPTPKMALDH1A1MEN1KMT2A | |
| Ethyl Isonipecotate SCHEMBL27812954 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Ethyl Isonipecotate SCHEMBL7622736 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ATMMEN1KMT2AL3MBTL1 | |
| SCHEMBL2235927 | 0.79 | MAPT (0.49) | MAPTPKMALDH1A1TSHR | |
| SCHEMBL8224141 | 0.79 | MAPT (0.49) | MAPTPKMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297346-A | PSYCHOACTIVE DRUGS BONDED TO NEUROPEPTIDES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1981-10-27 | — | — | US | claimed |
| US-5164386-A | Gastrointestinal and respiratory disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-11-17 | — | — | US | disclosed |
| EP-0404737-A2 | New R(-) 3-quinuclidinol derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-12-27 | — | — | EP | disclosed |
| US-4297346-A | PSYCHOACTIVE DRUGS BONDED TO NEUROPEPTIDES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1981-10-27 | — | — | US | disclosed |