⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22844805 | 1.00 | — | — | |
| SCHEMBL16248525 | 0.90 | NOD1 (0.36) | — | |
| SCHEMBL16248526 | 0.90 | NOD1 (0.36) | — | |
| SCHEMBL22844806 | 0.89 | CTSK (0.32) | — | |
| SCHEMBL19543400 | 0.89 | CTSK (0.32) | — | |
| SCHEMBL20099412 | 0.87 | NOD1 (0.34) | — | |
| SCHEMBL22479743 | 0.84 | FOLH1 (0.44) | — | |
| SCHEMBL21152873 | 0.84 | FOLH1 (0.44) | — | |
| SCHEMBL7602617 | 0.84 | FOLH1 (0.44) | — | |
| SCHEMBL12766314 | 0.84 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165987-A1 | PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE | Atoms for Cure GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2022258637-A1 | TRISLINKER-CONJUGATED DIMERIC LABELLING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM | Atoms for Cure GmbH (DE) | 2022-12-15 | — | — | WO | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-8486372-B2 | Cyclic azapeptides as integrin markers and methods of using | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-8133472-B2 | Cyclopeptides containing RGD mimetics as imaging markers for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-8043601-B2 | Cyclic azapeptides as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110256057-A1 | Cyclic Azapeptides as Integrin Markers and Methods of Using | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20100074844-A1 | Cyclopeptides Containing RGD Mimetics As Imaging Markers For Integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-7666392-B2 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-20090074664-A1 | CYCLIC AZAPEPTIDES AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2009-03-19 | — | — | US | disclosed |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-07-17 | — | — | US | disclosed |