Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060281 | 0.83 | EGLN1 (0.65) | EGLN1ALDH1A1PIM1 | |
| SCHEMBL4060285 | 0.83 | EGLN1 (0.65) | EGLN1ALDH1A1PIM1 | |
| SCHEMBL2201326 | 0.78 | EGLN1 (1.00) | EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL28055145 | 0.76 | ALDH1A1 (0.56) | EGLN1ALDH1A1PIM1 | |
| SCHEMBL13848806 | 0.75 | ALDH1A1 (0.52) | EGLN1ALDH1A1PIM1 | |
| SCHEMBL2200760 | 0.75 | EGLN1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL27679215 | 0.75 | NPC1 (0.54) | ALDH1A1NPC1RAB9A | |
| SCHEMBL1759043 | 0.75 | ALDH1A1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL7691064 | 0.74 | SLC2A1 (0.68) | EGLN1ALDH1A1NPC1RAB9A | |
| SCHEMBL2292957 | 0.74 | EGLN1 (0.86) | EGLN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384685-A | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2016-03-09 | — | — | CN | claimed |
| CN-102686566-A | Novel tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2012-09-19 | — | — | CN | claimed |
| CN-105384685-A | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2016-03-09 | — | — | CN | disclosed |
| CN-102686566-A | Novel tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof | POLICHEM SA | 2012-09-19 | — | — | CN | disclosed |