SCHEMBL1759043

SCHEMBL1759043

O=C(O)c1ccc2cccnc2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
EGLN1 Q9GZT9 14/20 0.66
LMNA P02545 1/20 0.59
ALOX12 P18054 1/20 0.59
KDM4E B2RXH2 1/20 0.56
KDM6B O15054 1/20 0.56
KDM6A O15550 1/20 0.56
TET3 O43151 1/20 0.56
KDM4A O75164 1/20 0.56
KDM4B O94953 1/20 0.56
KDM5C P41229 1/20 0.56
KDM4D Q6B0I6 1/20 0.56
TET2 Q6N021 1/20 0.56
ALKBH5 Q6P6C2 1/20 0.56
TET1 Q8NFU7 1/20 0.56
FTO Q9C0B1 1/20 0.56
KDM4C Q9H3R0 1/20 0.56
KDM2A Q9Y2K7 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KDM3A Q9Y4C1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9139640 0.98 ALDH1A1 (0.97) ALDH1A1EGLN1LMNAALOX12KDM4E
SCHEMBL27872555 0.87 ALDH1A1 (0.77) ALDH1A1EGLN1LMNAKDM4EHSP90AA1
SCHEMBL2143721 0.84 ALDH1A1 (0.73) ALDH1A1EGLN1LMNAKDM4EHSP90AA1
SCHEMBL253460 0.84 ALDH1A1 (0.73) ALDH1A1EGLN1
SCHEMBL8885906 0.84 ALDH1A1 (0.73) ALDH1A1EGLN1LMNAKDM4EHSP90AA1
SCHEMBL2143864 0.84 ALDH1A1 (0.73) ALDH1A1EGLN1LMNAKDM4EHSP90AA1
SCHEMBL31023212 0.83 ALDH1A1 (0.71) ALDH1A1EGLN1LMNAALOX12
SCHEMBL6487277 0.83 ALDH1A1 (0.71) ALDH1A1EGLN1LMNAALOX12
SCHEMBL69869 0.82 ALDH1A1 (0.70) ALDH1A1EGLN1LMNAALOX12KDM4E
SCHEMBL8885465 0.82 ALDH1A1 (0.70) ALDH1A1EGLN1LMNAKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR UNIV JIMEI (CN) 2025-09-04 US claimed
US-12377086-B2 Therapeutic methods, combinations and kits Sham, Yuk Yin (US) 2025-08-05 US claimed
WO-2025107568-A1 USE OF KYNURENIC ACID IN RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARING XOD INHIBITOR 集美大学 2025-05-30 WO claimed
CN-117883445-A Application of hyperuricemia resistance of canine uric acid and structural analogue thereof in preparation of XOD inhibitor 集美大学 2024-04-16 CN claimed
US-20220401432-A1 THERAPEUTIC METHODS, COMBINATIONS AND KITS REGENTS OF THE UNIVERSITY OF MINNESOTA 2022-12-22 US claimed
CN-115224271-A Method for in-situ construction of zinc cathode artificial interface layer by simple soaking method 南通大学 2022-10-21 CN claimed
US-20220280494-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2022-09-08 US claimed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
WO-2021041730-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2021-03-04 WO claimed
WO-2018057968-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
WO-2018057977-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
US-7989129-B2 Hydroxyquinoline containing photoconductors XEROX CORPORATION (US) 2011-08-02 US claimed
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO claimed
US-20090246662-A1 HYDROXYQUINOLINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
US-7479497-B2 Use of quinoline derivatives with anti-integrase effect and applications thereof BIOALLIANCE PHARMA SA (FR) 2009-01-20 US claimed
US-20080207673-A1 Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins XILINAS MICHEL 2008-08-28 US claimed
US-20080161350-A1 USE OF QUINOLINE DERIVATIVES WITH ANTI-INTEGRASE EFFECT AND APPLICATIONS THEREOF BIOALLIANCE PHARMA SA 2008-07-03 US claimed
WO-2006117660-A2 METHOD FOR TREATING CANCER, CORONARY, INFLAMMATORY AND MACULAR DISEASE, COMBINING THE MODULATION OF ZINC- AND/OR COPPER DEPENDENT PROTEINS CLIO PHARMACEUTICAL CORPORATION (US) 2006-11-09 WO claimed
US-20050261336-A1 Use of quinoline derivatives with anti-integrase effect and applications thereof BIOALLIANCE PHARMA SA 2005-11-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275954-A1 USE OF KYNURENIC ACID RESISTING HYPERURICEMIA AND STRUCTURAL ANALOG THEREOF IN PREPARATION OF XOD INHIBITOR XDH, DAO, KMO ALDH1A1 635/4885EGLN1 1642/4885LMNA 3160/4885
US-20220401432-A1 THERAPEUTIC METHODS, COMBINATIONS AND KITS MMP8, TLR7, GOT2 ALDH1A1 465/4885EGLN1 1717/4885LMNA 2213/4885
US-20050261336-A1 Use of quinoline derivatives with anti-integrase effect and applications thereof TYMP, CDK7, EIF2AK2 ALDH1A1 919/4885EGLN1 2892/4885LMNA 1234/4885
US-12377086-B2 Therapeutic methods, combinations and kits MMP8, TLR7, GOT2 ALDH1A1 465/4885EGLN1 1717/4885LMNA 2213/4885
US-20080161350-A1 USE OF QUINOLINE DERIVATIVES WITH ANTI-INTEGRASE EFFECT AND APPLICATIONS THEREOF TYMP, CDK7, MAVS ALDH1A1 853/4885EGLN1 2731/4885LMNA 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.