SCHEMBL27889043

SCHEMBL27889043

COc1cc2c(OC(C)=O)c(C)n(C(=O)c3ccc(C(F)F)s3)c2cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.41
PTGS2 P35354 2/20 0.41
ABCB11 O95342 1/20 0.34
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27789992 0.89 DAO (0.34) ABCB11DAO
SCHEMBL27905726 0.87 PTGS1 (0.40) PTGS1PTGS2ABCB11
SCHEMBL15062750 0.86 PTGS1 (0.40) PTGS1PTGS2ABCB11
SCHEMBL27889059 0.83 PTGS1 (0.43) PTGS1PTGS2ABCB11
SCHEMBL15062714 0.83 PTGS1 (0.40) PTGS1PTGS2ABCB11
SCHEMBL2012447 0.82 PTGS1 (0.64) PTGS1PTGS2ABCB11
SCHEMBL27889057 0.82 DAO (0.34) ABCB11DAO
SCHEMBL27790155 0.82 DAO (0.35) DAO
SCHEMBL15062607 0.81 PTGS1 (0.39) PTGS1PTGS2ABCB11
SCHEMBL5809374 0.78 PTGS2 (0.57) PTGS1PTGS2ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102850324-A Indole compounds MICROBIA INC 2013-01-02 CN disclosed