Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789986 | 0.89 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL27905754 | 0.88 | PTGS1 (0.43) | PTGS1PTGS2KMT2AABCB11ABCB1 | |
| SCHEMBL15062691 | 0.86 | PTGS1 (0.42) | PTGS1PTGS2KMT2AABCB11 | |
| SCHEMBL27889043 | 0.83 | PTGS1 (0.41) | PTGS1PTGS2ABCB11 | |
| SCHEMBL15062578 | 0.83 | PTGS1 (0.42) | PTGS1PTGS2KMT2AABCB11 | |
| SCHEMBL27889075 | 0.82 | TP53 (0.32) | PTGS1PTGS2KMT2AABCB11ABCB1 | |
| SCHEMBL2003893 | 0.82 | PTGS1 (0.67) | PTGS1PTGS2KMT2AABCB11ABCB1 | |
| SCHEMBL3005516 | 0.82 | — | — | |
| SCHEMBL15062558 | 0.81 | PTGS1 (0.41) | PTGS1PTGS2KMT2A | |
| SCHEMBL5809374 | 0.80 | PTGS2 (0.57) | PTGS1PTGS2KMT2AABCB11ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |