Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798784 | 0.91 | PTGS2 (0.66) | PTGS2PTGS1CYP1A2LMNANPSR1 | |
| SCHEMBL8579955 | 0.81 | LMNA (0.65) | PTGS2PTGS1CYP1A2LMNANPSR1 | |
| SCHEMBL2461597 | 0.80 | PTGS2 (0.86) | PTGS2PTGS1CYP1A2LMNANPSR1 | |
| SCHEMBL6423527 | 0.80 | PTGS2 (0.57) | PTGS2PTGS1CYP1A2LMNANPSR1 | |
| SCHEMBL27889059 | 0.80 | PTGS1 (0.43) | PTGS2PTGS1ABCB1ABCB11KMT2A | |
| SCHEMBL27905754 | 0.79 | PTGS1 (0.43) | PTGS2PTGS1ABCB1MAPTABCB11 | |
| SCHEMBL27647736 | 0.78 | P2RX4 (0.53) | PTGS2PTGS1CYP1A2LMNANPSR1 | |
| SCHEMBL27889043 | 0.78 | PTGS1 (0.41) | PTGS2PTGS1ABCB11 | |
| SCHEMBL5553765 | 0.78 | AKR1C3 (0.45) | PTGS2PTGS1LMNAABCB1ALDH1A1 | |
| SCHEMBL15062578 | 0.78 | PTGS1 (0.42) | PTGS2PTGS1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |