Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.55 |
| ▸ | CDK4 | P11802 | 2/20 | 0.55 |
| ▸ | CCND1 | P24385 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.55 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783567 | 0.98 | KIF11 (0.59) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL30655964 | 0.98 | KIF11 (0.59) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL12003837 | 0.96 | KIF11 (0.57) | KIF11CCNE2CDK4CCND1CCNE1 | |
| Carbazole SCHEMBL27955442 | 0.96 | ALDH1A1 (0.58) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL22136407 | 0.86 | KIF11 (0.60) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL28340739 | 0.86 | TDO2 (0.50) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL28564322 | 0.84 | KIF11 (0.58) | KIF11CCNE2CDK4CCND1CCNE1 | |
| Benzophenone SCHEMBL28341837 | 0.83 | PARP14 (0.50) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL25246575 | 0.82 | POLB (0.64) | KIF11CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1683249 | 0.82 | KIF11 (0.52) | KIF11ALDH1A1HSD17B10GPR3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476828-B | Method for producing polymer compound | 住友化学株式会社 | 2021-08-06 | — | — | CN | disclosed |
| CN-103250264-A | Light emitting element material and light emitting element | TORAY INDUSTRIES | 2013-08-14 | — | — | CN | disclosed |
| CN-102918677-A | Light emitting element | TORAY INDUSTRIES | 2013-02-06 | — | — | CN | disclosed |