Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159267 | 0.83 | KMT2A (0.49) | EPHX1EPHX2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL28524527 | 0.78 | GAA (0.42) | EPHX1EPHX2APOBEC3AAPOBEC3GNAAA | |
| SCHEMBL6007931 | 0.78 | KMT2A (0.45) | EPHX1EPHX2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL7174165 | 0.77 | EPHX1 (0.37) | EPHX1EPHX2APOBEC3AAPOBEC3GNAAA | |
| SCHEMBL8158699 | 0.77 | EPHX1 (0.62) | EPHX1EPHX2NAAAHTTTET2 | |
| SCHEMBL28574621 | 0.77 | — | — | |
| SCHEMBL12335551 | 0.77 | EPHX1 (0.50) | EPHX1NAAAHTTGAAALDH1A1 | |
| SCHEMBL11186733 | 0.76 | NAAA (0.38) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL22699875 | 0.76 | EPHX1 (0.66) | EPHX1EPHX2NAAAHTTTET2 | |
| SCHEMBL5283279 | 0.75 | EPHX1 (0.52) | EPHX1EPHX2NAAAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712628-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | disclosed |
| CN-102712623-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-03 | — | — | CN | disclosed |