Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890002 | 0.77 | EPHX1 (0.43) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL28524527 | 0.76 | GAA (0.42) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL11038356 | 0.75 | GAA (0.53) | HTTKDM4ESMN1; SMN2EPHX2GAA | |
| SCHEMBL7875267 | 0.74 | EPHX1 (0.53) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL28574621 | 0.74 | — | — | |
| SCHEMBL11186733 | 0.73 | NAAA (0.38) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL2159267 | 0.73 | KMT2A (0.49) | EPHX1APOBEC3AAPOBEC3GEPHX2GAA | |
| SCHEMBL28363860 | 0.72 | TPSAB1 (0.41) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL27879381 | 0.70 | EPHX1 (0.53) | EPHX1APOBEC3AAPOBEC3GNAAAHTT | |
| SCHEMBL242453 | 0.70 | NAAA (0.42) | EPHX1APOBEC3AAPOBEC3GNAAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289935-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | claimed |
| WO-2001092212-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2001-12-06 | — | — | WO | claimed |