SCHEMBL2789147

SCHEMBL2789147

O=C(O)c1cc(-c2ccc(F)cc2)ccc1S

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 2/20 0.52
BAD Q92934 2/20 0.52
DCLRE1B Q9H816 2/20 0.46
ACMSD Q8TDX5 4/20 0.46
DHFR P00374 2/20 0.46
MCL1 Q07820 2/20 0.46
HNF4A P41235 2/20 0.46
KDM4E B2RXH2 2/20 0.46
KMT2A Q03164 2/20 0.46
GFER P55789 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
LMNA P02545 1/20 0.45
TTR P02766 1/20 0.45
ALB P02768 1/20 0.45
HMGB1 P09429 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2789149 0.85 ACMSD (0.63) DCLRE1BACMSDDHFRMCL1HNF4A
SCHEMBL1424485 0.84 KEAP1 (0.59) BCL2L1BADDCLRE1BACMSDDHFR
SCHEMBL14252284 0.82 BCL2L1 (0.57) BCL2L1BADDCLRE1BACMSDDHFR
SCHEMBL3062072 0.81 BCL2L1 (0.55) BCL2L1BADACMSDDHFRMCL1
SCHEMBL330405 0.79 ACMSD (0.72) BCL2L1BADACMSDDHFRMCL1
SCHEMBL3690106 0.78 ACMSD (0.70) BCL2L1BADACMSDDHFRMCL1
SCHEMBL3695268 0.78 ACMSD (0.70) BCL2L1BADACMSDDHFRMCL1
SCHEMBL3128937 0.78 GRIK1 (0.55) BCL2L1BADACMSDDHFRMCL1
SCHEMBL2789012 0.78 KMT2A (0.78) BCL2L1BADACMSDDHFRMCL1
SCHEMBL7326903 0.78 MCL1 (0.54) BCL2L1BADACMSDDHFRMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100152455-A1 ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2010-06-17 US disclosed
EP-2092040-A1 ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMIESCENT DEVICE USING THE SAME Gracel Display Inc. (KR) 2009-08-26 EP disclosed
WO-2008082249-A1 ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMIESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2008-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152455-A1 ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EPCAM, ORC3, L1CAM BCL2L1 2497/4885BAD 2881/4885DCLRE1B 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.