Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.63 |
| ▸ | HNF4A | P41235 | 2/20 | 0.63 |
| ▸ | DHFR | P00374 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.61 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791080 | 0.85 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL2789147 | 0.85 | BCL2L1 (0.52) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL30616786 | 0.81 | ACMSD (0.70) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL68982 | 0.81 | ACMSD (0.70) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL2789084 | 0.80 | AKR1C2 (0.57) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| Hydrochloric Acid SCHEMBL11162468 | 0.79 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| Methane SCHEMBL29008389 | 0.79 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL21879680 | 0.79 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| Water SCHEMBL29008379 | 0.79 | ACMSD (0.68) | ACMSDHNF4ADHFRMCL1DCLRE1A | |
| SCHEMBL23143193 | 0.78 | ACMSD (1.00) | ACMSDHNF4ADHFRMCL1GSTA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152455-A1 | ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | GRACEL DISPLAY INC. (KR) | 2010-06-17 | — | — | US | disclosed |
| CN-1872846-B | Method of preparing 2-benzothiazepines derivative | UBE INDUSTRIES | 2010-06-16 | — | — | CN | disclosed |
| US-7671195-B2 | Process for preparing dibenzothiazepine compounds | ASTRAZENECA UK LIMITED (GB) | 2010-03-02 | — | — | US | disclosed |
| CN-100577653-C | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES | 2010-01-06 | — | — | CN | disclosed |
| EP-2092040-A1 | ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMIESCENT DEVICE USING THE SAME | Gracel Display Inc. (KR) | 2009-08-26 | — | — | EP | disclosed |
| EP-2080795-A1 | Electroluminescent device using electroluminescent compounds | Gracel Display Inc. (KR) | 2009-07-22 | — | — | EP | disclosed |
| US-20090165860-A1 | Electroluminescent device using electroluminescent compounds | GRACEL DISPLAY INC. (KR) | 2009-07-02 | — | — | US | disclosed |
| US-20090165860-A1 | Electroluminescent device using electroluminescent compounds | GRACEL DISPLAY INC. (KR) | 2009-07-02 | — | — | US | disclosed |
| US-20090078317-A1 | Organometalic compounds for electroluminescence and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-03-26 | — | — | US | disclosed |
| US-20090078317-A1 | Organometalic compounds for electroluminescence and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-03-26 | — | — | US | disclosed |
| US-7314930-B2 | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| WO-2007102352-A2 | PROCESS FOR PREPARING DIBENZOTHIAZEPINE COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 2007-09-13 | — | — | WO | disclosed |
| US-20070203336-A1 | Process for preparing dibenzothiazepine compounds | ASTRAZENECA UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| CN-1872846-A | Method of preparing 2-benzothiazepines derivative | UBE INDUSTRIES (JP) | 2006-12-06 | — | — | CN | disclosed |
| US-20060173178-A1 | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2006-08-03 | — | — | US | disclosed |
| CN-1810792-A | Process for preparing dibenzothiazepine * derivatives | UBE INDUSTRIES (JP) | 2006-08-02 | — | — | CN | disclosed |
| US-7045621-B1 | Process for producing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| CN-1247556-C | Process for preparing dibenzothiazepine * derivatives | UBE INDUSTRIES (JP) | 2006-03-29 | — | — | CN | disclosed |
| CN-1367782-A | Process for preparing dibenzothiazepine * derivatives | UBE INDUSTRIES (JP) | 2002-09-04 | — | — | CN | disclosed |
| EP-1201663-A1 | PROCESS FOR PRODUCING DIBENZOTHIAZEPINE DERIVATIVES | Ube Industries, Ltd. (JP) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173178-A1 | Process for preparing dibenzothiazepine derivatives | TPMT, BBOX1, NISCH | ACMSD 128/4885HNF4A 2148/4885DHFR 55/4885 |
| US-20100152455-A1 | ORGANOMETALIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | EPCAM, ORC3, L1CAM | ACMSD 1361/4885HNF4A 2030/4885DHFR 2390/4885 |
| US-20090078317-A1 | Organometalic compounds for electroluminescence and organic electroluminescent device using the same | OCIAD1, L1CAM, OCIAD2 | ACMSD 283/4885HNF4A 1687/4885DHFR 3589/4885 |
| US-20070203336-A1 | Process for preparing dibenzothiazepine compounds | TST, ADH1C, ADH5 | ACMSD 4/4885HNF4A 2669/4885DHFR 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.