Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891731 | 0.93 | KDM4E (0.45) | MEN1KMT2ACYP19A1KDM4EUTS2R | |
| SCHEMBL27908714 | 0.90 | SLC6A4 (0.44) | KMT2ASLC6A4SLC6A2CACNA2D1HRH1 | |
| SCHEMBL27908713 | 0.85 | RCE1 (0.42) | KDM4ESLC6A4SLC6A2CACNA2D1HRH1 | |
| SCHEMBL27891719 | 0.83 | SLC6A4 (0.41) | MEN1KMT2AKDM4ESLC6A4SLC6A2 | |
| SCHEMBL27908719 | 0.83 | MEN1 (0.42) | MEN1KMT2ACYP19A1KDM4ESLC6A4 | |
| SCHEMBL27891783 | 0.82 | CYP19A1 (0.45) | MEN1KMT2ACYP19A1KDM4EUTS2R | |
| SCHEMBL27891792 | 0.78 | MCL1 (0.46) | MEN1KMT2ACYP19A1KDM4EUTS2R | |
| SCHEMBL27891762 | 0.77 | CYP19A1 (0.47) | MEN1KMT2ACYP19A1KDM4EUTS2R | |
| SCHEMBL27891728 | 0.77 | RCE1 (0.47) | MEN1KMT2AKDM4ELMNAHTT | |
| SCHEMBL28378585 | 0.76 | CXCR4 (0.46) | CYP19A1KDM4ELMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |