Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891748 | 0.93 | MEN1 (0.44) | KDM4ECYP19A1MEN1KMT2AUTS2R | |
| SCHEMBL27891719 | 0.88 | SLC6A4 (0.41) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL27891728 | 0.84 | RCE1 (0.47) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL27908714 | 0.82 | SLC6A4 (0.44) | KMT2ASIGMAR1 | |
| SCHEMBL27891723 | 0.82 | KDM4E (0.43) | KDM4ECYP19A1MEN1KMT2AATM | |
| SCHEMBL27891762 | 0.80 | CYP19A1 (0.47) | KDM4ECYP19A1MEN1KMT2AUTS2R | |
| SCHEMBL27891783 | 0.78 | CYP19A1 (0.45) | KDM4ECYP19A1MEN1KMT2AUTS2R | |
| SCHEMBL27891759 | 0.77 | MCL1 (0.48) | KDM4ECYP19A1MEN1KMT2AUTS2R | |
| SCHEMBL27908713 | 0.77 | RCE1 (0.42) | KDM4EHSD17B10L3MBTL1HTTALDH1A1 | |
| SCHEMBL27908719 | 0.75 | MEN1 (0.42) | KDM4ECYP19A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |