Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908714 | 0.94 | SLC6A4 (0.44) | SLC6A4SLC6A2HRH1SIGMAR1KMT2A | |
| SCHEMBL27891731 | 0.88 | KDM4E (0.45) | SIGMAR1KMT2AMEN1LMNAPOLB | |
| SCHEMBL27891748 | 0.83 | MEN1 (0.44) | SLC6A4SLC6A2HRH1KMT2AMEN1 | |
| SCHEMBL27908716 | 0.83 | ABCB1 (0.41) | SLC6A4SLC6A2HRH1SIGMAR1KMT2A | |
| SCHEMBL27891728 | 0.82 | RCE1 (0.47) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL27908727 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A2HRH1SIGMAR1KMT2A | |
| SCHEMBL27908744 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A2HRH1SIGMAR1KMT2A | |
| SCHEMBL27891724 | 0.79 | MCL1 (0.44) | SLC6A4SLC6A2HRH1SIGMAR1KMT2A | |
| SCHEMBL27908713 | 0.78 | RCE1 (0.42) | SLC6A4SLC6A2HRH1KDM4ECHRM2 | |
| SCHEMBL27921260 | 0.77 | SIGMAR1 (0.46) | SIGMAR1CNR2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |