Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908713 | 0.92 | RCE1 (0.42) | RCE1KDM4EEGFRALDH1A1HSD17B10 | |
| SCHEMBL27891731 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL27891719 | 0.82 | SLC6A4 (0.41) | RCE1KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL27891741 | 0.77 | RCE1 (0.41) | RCE1KDM4EEGFRALDH1A1HSD17B10 | |
| SCHEMBL27891748 | 0.77 | MEN1 (0.44) | KDM4EALDH1A1KMT2APOLBLMNA | |
| SCHEMBL27908714 | 0.77 | SLC6A4 (0.44) | KMT2A | |
| SCHEMBL3333405 | 0.77 | GPR3 (0.52) | KDM4EALDH1A1HSD17B10KMT2ACXCR4 | |
| SCHEMBL27908739 | 0.75 | SLC6A4 (0.43) | RCE1KDM4EEGFRALDH1A1HSD17B10 | |
| SCHEMBL27899830 | 0.73 | GPR3 (0.50) | KDM4EALDH1A1HSD17B10KMT2ACXCR4 | |
| SCHEMBL31402885 | 0.70 | UTS2R (0.42) | RCE1KDM4EALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | claimed |