Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615550 | 0.86 | GLA (0.47) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11616957 | 0.80 | SMN1; SMN2 (0.39) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18366016 | 0.79 | ALDH1A1 (0.50) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11617013 | 0.78 | LMNA (0.38) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11616890 | 0.75 | ALDH1A1 (0.36) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5878432 | 0.75 | LMNA (0.49) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11618755 | 0.74 | ALDH1A1 (0.43) | ALDH1A1RAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL28050025 | 0.73 | ALDH1A1 (0.42) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11581563 | 0.71 | LMNA (0.56) | GLAALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL16328893 | 0.71 | LMNA (0.37) | GLAALDH1A1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958920-A | Metronidazole esters for the treatment of rosacea | GALDERMA RES & DEV | 2013-03-06 | — | — | CN | disclosed |