Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL27295473 | 0.84 | ALDH1A1 (0.37) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL28060400 | 0.82 | LMNA (0.35) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11617013 | 0.82 | LMNA (0.38) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL9467304 | 0.82 | LMNA (0.35) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL16328893 | 0.82 | LMNA (0.37) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11616890 | 0.79 | ALDH1A1 (0.36) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL27381848 | 0.78 | ALDH1A1 (0.33) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11618755 | 0.78 | ALDH1A1 (0.43) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11882011 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL28050025 | 0.77 | ALDH1A1 (0.42) | LMNAALDH1A1MAPK1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650839-A | Oil field corrosion inhibition bactericide and preparation method thereof | CHINA NAT OFFSHORE OIL CORP | 2015-05-27 | — | — | CN | claimed |
| EP-0324691-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | claimed |
| CN-105979933-A | Pharmaceutical preparation, method for the production thereof and use thereof | 因凡瑞斯有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105348200-A | Environment-friendly method for metronidazole synthesis | WUHAN WUYAO PHARMACEUTICAL CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-104650839-A | Oil field corrosion inhibition bactericide and preparation method thereof | CHINA NAT OFFSHORE OIL CORP | 2015-05-27 | — | — | CN | disclosed |
| CN-103476926-A | Compositions and methods for improved isoprene production using two types of IspG enzymes | DANISCO US INC | 2013-12-25 | — | — | CN | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| CN-103403145-A | Biological production of pentose sugars using recombinant cells | DANISCO US INC | 2013-11-20 | — | — | CN | disclosed |
| US-7053114-B2 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | SUGEN, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-6797725-B2 | SUCH AS 4-METHYL-5-(2-OXO-1,2-DIHYDROINDOL-3-YLILDENEMETHYL)-1H-PYRROLE-2-CARBOXYLIC ACID FOR PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED CELLULAR DISORDERS; ANTICANCER AGENTS | SUGEN, INC. | 2004-09-28 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| CN-1035288-A | The preparation method of 1-hydroxyalkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | disclosed |
| CN-1035111-A | Hydroxyalkyl agent preparation method, gained new preparation and application thereof like this | RHONE POULENC SANTE (FR) | 1989-08-30 | — | — | CN | disclosed |
| US-4080340-A | Nitroimidazoles | MERCK & CO., INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4010176-A | Isoxazole substituted nitroimidazoles | MERCK & CO., INC. (US) | 1977-03-01 | — | — | US | disclosed |
| US-3910925-A | {8 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl{9 benzo(b)pyridyloxy ethers | SEARLE & CO | 1975-10-07 | — | — | US | disclosed |