Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703710 | 0.84 | LMNA (0.46) | LMNATHRBTDP1MAPTPOLB | |
| SCHEMBL3592533 | 0.82 | LMNA (0.57) | LMNATDP1MAPTKDM4EGLA | |
| SCHEMBL273112 | 0.80 | LMNA (0.45) | LMNATHRBTDP1MAPTKDM4E | |
| SCHEMBL9955398 | 0.80 | LMNA (0.52) | LMNAMAPTKDM4EGLAPOLB | |
| Hydrochloric Acid SCHEMBL273187 | 0.79 | LMNA (0.44) | LMNATHRBTDP1MAPTKDM4E | |
| SCHEMBL11066636 | 0.79 | TDP1 (0.55) | LMNATDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL27876663 | 0.79 | NLRP3 (0.42) | LMNAMAPTKDM4EHTTPOLB | |
| SCHEMBL21631638 | 0.78 | LMNA (0.45) | LMNATHRBMAPTKDM4EHTT | |
| SCHEMBL1346377 | 0.77 | LMNA (0.52) | LMNAMAPTKDM4EGLAPOLB | |
| SCHEMBL31657581 | 0.77 | LMNA (0.52) | LMNATDP1MAPTKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102757434-B | Preparation method for industrial amplified production of anagrelide hydrochloride active pharmaceutical ingredient | HEILONGJIANG TIMEHOME PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-102757434-A | Preparation method for industrial amplified production of anagrelide hydrochloride active pharmaceutical ingredient | HEILONGJIANG TIMEHOME PHARMACEUTICAL CO LTD | 2012-10-31 | — | — | CN | disclosed |