Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893370 | 0.84 | LMNA (0.52) | LMNAPKML3MBTL1THRBPOLB | |
| SCHEMBL13405571 | 0.83 | KMT2A (0.48) | LMNAMEN1KMT2APKML3MBTL1 | |
| SCHEMBL9704149 | 0.80 | HPGD (0.47) | LMNAMEN1HPGDKMT2APKM | |
| SCHEMBL9703477 | 0.80 | MEN1 (0.50) | LMNAMEN1HPGDKMT2APKM | |
| SCHEMBL2024670 | 0.78 | NLRP3 (0.52) | LMNAMEN1KMT2APKMTSHR | |
| SCHEMBL3706025 | 0.78 | L3MBTL1 (0.69) | LMNAMEN1HPGDKMT2APKM | |
| SCHEMBL11015444 | 0.77 | TDP1 (0.53) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL30623198 | 0.75 | PKM (0.67) | LMNAMEN1HPGDKMT2APKM | |
| SCHEMBL9703402 | 0.75 | PKM (0.67) | LMNAMEN1HPGDKMT2APKM | |
| SCHEMBL273112 | 0.74 | LMNA (0.45) | LMNAMEN1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |