Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 11/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399069 | 0.89 | NOTUM (0.46) | NOTUMALDH1A1 | |
| SCHEMBL1535851 | 0.73 | — | — | |
| SCHEMBL10413341 | 0.73 | NOTUM (0.47) | NOTUMNAMPTDPP8DPP9DPP7 | |
| SCHEMBL27622745 | 0.72 | SLC18A3 (0.60) | NAMPTALDH1A1 | |
| SCHEMBL27570333 | 0.72 | SIGMAR1 (0.51) | ALDH1A1 | |
| SCHEMBL27648479 | 0.72 | BLM (0.57) | ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28284496 | 0.71 | NOTUM (0.48) | NOTUMALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8471853 | 0.71 | NOTUM (0.49) | NOTUMALDH1A1 | |
| SCHEMBL11435778 | 0.71 | KMT2A (0.52) | ALDH1A1CYP2D6 | |
| SCHEMBL10850124 | 0.71 | ALDH1A1 (0.43) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781915-A | Diacylglycerol acyltransferase inhibitors | PIRAMAL LIFE SCIENCES LTD | 2012-11-14 | — | — | CN | disclosed |