Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27877844 | 1.00 | UCHL1 (0.40) | UCHL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29771950 | 0.88 | UCHL1 (0.41) | UCHL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1868501 | 0.88 | UCHL1 (0.41) | UCHL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1868500 | 0.88 | UCHL1 (0.41) | UCHL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1873295 | 0.88 | UCHL1 (0.41) | UCHL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29771900 | 0.81 | TAS1R3 (0.43) | UCHL1KMT2A | |
| SCHEMBL13974108 | 0.81 | TAS1R3 (0.43) | UCHL1KMT2A | |
| SCHEMBL13974252 | 0.81 | TAS1R3 (0.43) | UCHL1KMT2A | |
| SCHEMBL27906103 | 0.80 | PDPK1 (0.49) | NPC1RAB9AKMT2AMEN1HTT | |
| SCHEMBL22501405 | 0.74 | GID4 (0.41) | NPC1KMT2AMEN1HTTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753022-A | Selective heterocyclic sphingosine 1-phosphate receptor modulators | RECEPTOS INC | 2012-10-24 | — | — | CN | disclosed |