Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24380112 | 0.93 | SMN1; SMN2 (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27878247 | 0.86 | LMNA (0.41) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902902 | 0.84 | LMNA (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902905 | 0.84 | LMNA (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902904 | 0.82 | NR5A1 (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902903 | 0.82 | DRD4 (0.46) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902908 | 0.81 | NR5A1 (0.50) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902919 | 0.81 | NR5A1 (0.50) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17465611 | 0.81 | LMNA (0.62) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16902912 | 0.81 | NR5A1 (0.50) | LMNAMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727470-B | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2014-02-19 | — | — | CN | disclosed |
| CN-102727470-A | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2012-10-17 | — | — | CN | disclosed |