Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233153 | 0.77 | GAA (0.50) | PIK3CAPIK3CDPIK3R2BRD4PIK3CB | |
| SCHEMBL2235379 | 0.74 | STK17B (0.39) | MAPTRAB9ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL2233188 | 0.72 | RAB9A (0.38) | MAPTRAB9AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2233024 | 0.71 | KDM4E (0.37) | MAPTRAB9AMEN1KMT2ATSHR | |
| SCHEMBL2299923 | 0.71 | PTK2 (0.50) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL20895103 | 0.68 | CSNK2A1 (0.49) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL2232410 | 0.68 | BRAF (0.42) | MAPTRAB9AKMT2ATSHRALDH1A1 | |
| SCHEMBL14125075 | 0.68 | KDM4E (0.39) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11496084 | 0.66 | ALDH1A1 (0.62) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27815576 | 0.65 | PIK3CA (0.46) | PIK3CAMAPTRAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741256-A | Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase | HANMI PHARM IND CO LTD | 2012-10-17 | — | — | CN | claimed |
| CN-102741256-B | Protein kinase is had to the bicyclic heteroaryl derivative of inhibit activities | HANMI PHARM. CO.,LTD. (KR) | 2015-12-02 | — | — | CN | disclosed |
| CN-102741256-A | Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase | HANMI PHARM IND CO LTD | 2012-10-17 | — | — | CN | disclosed |