Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896441 | 0.83 | EPHX2 (0.38) | ALDH1A1GAASMN1; SMN2DPP4HPGD | |
| SCHEMBL27896402 | 0.78 | ACE (0.36) | — | |
| SCHEMBL27879636 | 0.77 | CHRM2 (0.37) | ADH1BADH1CADH1ADPP4PREP | |
| SCHEMBL7408815 | 0.77 | POLB (0.36) | ADH1BADH1CADH1AADH4DPP4 | |
| SCHEMBL28826381 | 0.77 | DPP4 (0.40) | DPP4PREPFAP | |
| SCHEMBL27879619 | 0.76 | TSHR (0.44) | TSHRALDH1A1GAAADH1BADH1C | |
| SCHEMBL28054834 | 0.75 | DPP4 (0.55) | DPP4PREPFAP | |
| SCHEMBL28054657 | 0.75 | DPP4 (0.55) | DPP4PREPFAP | |
| SCHEMBL21696767 | 0.74 | ALDH1A1 (0.48) | TSHRALDH1A1GAASMN1; SMN2HSD11B1 | |
| SCHEMBL29091404 | 0.73 | DPP4 (0.33) | ADH1BADH1CADH1AADH4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |