Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896386 | 0.83 | TSHR (0.44) | SMN1; SMN2DPP4GAAHPGDALDH1A1 | |
| SCHEMBL27879636 | 0.81 | CHRM2 (0.37) | DPP4 | |
| SCHEMBL27896402 | 0.75 | ACE (0.36) | — | |
| SCHEMBL28826381 | 0.74 | DPP4 (0.40) | EPHX2DPP4POLB | |
| SCHEMBL7408815 | 0.72 | POLB (0.36) | DPP4POLB | |
| SCHEMBL771581 | 0.71 | EPHX2 (0.53) | EPHX2EPHX1 | |
| SCHEMBL27896434 | 0.71 | CYP3A4 (0.39) | HSD17B10DPP4 | |
| SCHEMBL28801602 | 0.71 | PREP (0.42) | DPP4 | |
| SCHEMBL28054834 | 0.70 | DPP4 (0.55) | DPP4 | |
| SCHEMBL28054657 | 0.70 | DPP4 (0.55) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |