Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896387 | 0.77 | TSHR (0.40) | TSHRGAAHSD11B1ALDH1A1HSD11B2 | |
| SCHEMBL27896386 | 0.76 | TSHR (0.44) | TSHRGAAHSD11B1ALDH1A1HSD11B2 | |
| SCHEMBL27896445 | 0.74 | ATM (0.30) | — | |
| SCHEMBL28054810 | 0.68 | PIK3CD (0.55) | PIK3CDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL27879637 | 0.65 | CTSS (0.42) | HSD11B1PIK3CDALDH1A1 | |
| SCHEMBL28862004 | 0.65 | — | — | |
| SCHEMBL19271816 | 0.63 | HSD11B1 (0.69) | TSHRHSD11B1ALDH1A1HSD11B2CHRNB2 | |
| SCHEMBL9667146 | 0.63 | TSHR (0.96) | TSHRGAAHSD11B1ALDH1A1HSD11B2 | |
| SCHEMBL27896451 | 0.62 | — | — | |
| SCHEMBL21696865 | 0.61 | TSHR (0.45) | TSHRGAAHSD11B1ALDH1A1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |