Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 10/20 | 0.40 |
| ▸ | FAP | Q12884 | 6/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28826381 | 0.83 | DPP4 (0.40) | PREPDPP4FAP | |
| SCHEMBL29091403 | 0.80 | DPP4 (0.34) | PREPDPP4FAPDPP7 | |
| SCHEMBL27857100 | 0.80 | ALDH1A1 (0.39) | PREPDPP4FAPDPP7 | |
| SCHEMBL27879615 | 0.80 | PREP (0.35) | PREPDPP4FAPDPP7HCRTR2 | |
| SCHEMBL19104795 | 0.79 | SMN1; SMN2 (0.44) | PREPDPP4FAPDPP7HCRTR2 | |
| SCHEMBL7408815 | 0.77 | POLB (0.36) | DPP4 | |
| SCHEMBL27879636 | 0.77 | CHRM2 (0.37) | PREPDPP4FAPCHRM2CHRM4 | |
| SCHEMBL27896393 | 0.76 | GAA (0.43) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27879604 | 0.73 | NAMPT (0.35) | DPP4HCRTR2 | |
| SCHEMBL27896434 | 0.73 | CYP3A4 (0.39) | PREPDPP4FAPDPP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |