Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.55 |
| ▸ | RELA | Q04206 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139108 | 0.86 | APP (0.71) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL5691159 | 0.83 | APP (0.77) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL10706363 | 0.83 | APP (0.68) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL4804942 | 0.83 | APP (0.68) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL4797697 | 0.83 | NFKB1 (0.68) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL3187010 | 0.81 | KDM4E (0.68) | KDM4ENFKB1NFKB2RELANPC1 | |
| Dimethylamine SCHEMBL27718704 | 0.81 | APP (0.72) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL27897607 | 0.81 | AHR (0.57) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL10710841 | 0.81 | AHR (0.57) | AHRKDM4ENFKB1NFKB2RELA | |
| SCHEMBL2138056 | 0.81 | KDM4E (0.58) | KDM4ENFKB1NFKB2RELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992291-B | Method for synthesizing 2-substituted benzothiazole derivative | NANJING TECH UNIVERSITY (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-102977051-A | Method for synthesizing 2-substituted benzothiazole derivative | UNIV HUNAN | 2013-03-20 | — | — | CN | disclosed |