Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386954 | 0.78 | CYP1A2 (0.53) | HTT | |
| SCHEMBL27797840 | 0.77 | CDC25B (0.44) | CDC25BALDH1A1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL27915736 | 0.76 | CDC25B (0.41) | CDC25BALDH1A1HSD17B10TTRTSHR | |
| SCHEMBL2220408 | 0.74 | TTR (0.41) | CDC25BTTRNSD2 | |
| SCHEMBL111776 | 0.72 | HSD11B1 (0.49) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL5946756 | 0.70 | ALDH1A1 (0.65) | CDC25BALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL9241852 | 0.69 | NSD2 (0.50) | TTRTSHRSMN1; SMN2NSD2 | |
| SCHEMBL8839050 | 0.69 | TTR (0.45) | TTRNSD2 | |
| SCHEMBL28718534 | 0.69 | TTR (0.45) | ALDH1A1TTRSMN1; SMN2HSD11B1NSD2 | |
| SCHEMBL1525888 | 0.68 | TTR (0.78) | ALDH1A1HSD17B10TTRTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118139851-A | Antitumor compounds | 法马马有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-110650954-B | anticancer compounds | 法马马有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-110650954-A | Anticancer compounds | 法马马有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-103038240-A | Synthetic method for preparing ecteinascidin compounds | PHARMA MAR SA | 2013-04-10 | — | — | CN | disclosed |