Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27898331

N.O=S(=O)(OCCO)c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 1/20 0.43
ALDH1A1 P00352 7/20 0.42
RECQL P46063 1/20 0.42
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR6 P50406 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
PSIP1 O75475 1/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30555660 0.98 PARL (0.44) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL3447513 0.98 PARL (0.44) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL10866994 0.96 PARL (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL28496864 0.96 PARL (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
Diphenylsulfane SCHEMBL28640213 0.88 MMP13 (0.40) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL16899911 0.87 ALDH1A1 (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL907441 0.87 ALDH1A1 (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL11561329 0.87 ALDH1A1 (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL9861005 0.87 ALDH1A1 (0.43) PARLALDH1A1RECQLTSHRSMN1; SMN2
SCHEMBL4685859 0.86 PARL (0.42) PARLALDH1A1RECQLTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103030912-A Method for preparing composite water self-absorbent containing N, N, N-4 (2-hydroxyethyl) hyamine UNIV NANJING FORESTRY 2013-04-10 CN disclosed