Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473573 | 0.84 | TRPA1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL474234 | 0.84 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27916466 | 0.81 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27898682 | 0.80 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27916452 | 0.79 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL16003853 | 0.79 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27986837 | 0.78 | LTA4H (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL3140677 | 0.78 | ALDH1A1 (0.52) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28814662 | 0.78 | LTA4H (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL2380192 | 0.77 | HSD17B10 (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906617-A | Modulators of HEC1 activity and methods thereof | 泰纬生命科技股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103038231-B | Modulators of HEC1 activity and methods thereof | Taivex Therapeutics Corp. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103038231-A | Modulators of HEC1 activity and methods thereof | TAIVEX THERAPEUTICS INC | 2013-04-10 | — | — | CN | disclosed |