Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SDCBP | O00560 | 7/20 | 0.38 |
| ▸ | SDC2 | P34741 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19222240 | 0.83 | ALOX15 (0.39) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL27881767 | 0.83 | SDCBP (0.35) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL20425363 | 0.81 | KDM4E (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL2257304 | 0.81 | KDM4E (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL20766605 | 0.81 | ALOX15 (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL20766604 | 0.81 | ALOX15 (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL25907886 | 0.80 | ALOX15 (0.37) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL17343919 | 0.80 | ALOX15 (0.37) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL2250406 | 0.79 | MEN1 (0.48) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL27899007 | 0.78 | HTT (0.40) | MAPTSMN1; SMN2KDM4ESDCBPSDC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822165-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2012-12-12 | — | — | CN | disclosed |