Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882707 | 0.93 | HDAC2 (0.41) | MAOBTAAR1SIGMAR1HDAC2TDP2 | |
| SCHEMBL27882739 | 0.89 | MAOB (0.42) | MAOBTAAR1TDP2IDO1AGXT | |
| SCHEMBL27900190 | 0.82 | NPC1 (0.41) | MAOBTAAR1TDP2MEN1NPC1 | |
| SCHEMBL1044622 | 0.80 | TAAR1 (0.59) | MAOBTAAR1SIGMAR1IDO1AGXT | |
| SCHEMBL27900219 | 0.79 | MAOB (0.65) | MAOBTAAR1 | |
| SCHEMBL27900194 | 0.79 | TAAR1 (0.65) | MAOBTAAR1AGXT | |
| SCHEMBL5543001 | 0.79 | FFAR1 (0.50) | MAOBTAAR1HDAC2IDO1AGXT | |
| SCHEMBL13682551 | 0.77 | ALDH1A1 (0.52) | MAOBTDP2IDO1MEN1NPC1 | |
| SCHEMBL27900187 | 0.76 | TAAR1 (0.45) | TAAR1SIGMAR1HDAC2NPC1ALDH1A1 | |
| SCHEMBL1005011 | 0.75 | TAAR1 (0.52) | TAAR1SIGMAR1IDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277740-B | Antituberculous composition comprising azole compound | OTSUKA PHARMA CO LTD | 2012-12-05 | — | — | CN | disclosed |