Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900467 | 0.76 | MAPT (0.50) | ALDH1A1MAPTHTTGAADHODH | |
| SCHEMBL27988467 | 0.73 | MAPT (0.47) | ALDH1A1MAPTHTTGAADHODH | |
| SCHEMBL587239 | 0.72 | HSD17B10 (0.40) | ALDH1A1MAPTL3MBTL1TDP1ALOX12 | |
| SCHEMBL28378687 | 0.72 | MAPT (0.45) | ALDH1A1MAPTHTTGAANPC1 | |
| O-Xylene SCHEMBL2065413 | 0.71 | TSHR (0.48) | ALDH1A1MAPTHTTHPGDKDM4E | |
| SCHEMBL1485712 | 0.71 | MAPT (0.59) | ALDH1A1MAPTHTTGAANPC1 | |
| SCHEMBL29617680 | 0.71 | MAPT (0.52) | ALDH1A1MAPTHTTGAANPC1 | |
| SCHEMBL8984386 | 0.71 | MAPT (0.52) | ALDH1A1MAPTHTTGAANPC1 | |
| SCHEMBL28235239 | 0.70 | HTT (0.44) | MAPTHTTGAADHODHNPC1 | |
| Hydrochloric Acid SCHEMBL2866031 | 0.69 | MAPT (0.57) | ALDH1A1MAPTHTTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114521196-A | Bifunctional group degradation agent and use method thereof | 诺华股份有限公司 | 2022-05-20 | — | — | CN | disclosed |