Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28229486 | 0.84 | F2R (0.55) | ALDH1A1LMNAHTTF2RCLCN2 | |
| SCHEMBL27900511 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTF2RCLCN2 | |
| SCHEMBL11207843 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTF2RCLCN2 | |
| SCHEMBL5724688 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTF2RCLCN2 | |
| SCHEMBL9623495 | 0.80 | EPHX2 (0.47) | ALDH1A1LMNATSHRTP53HDAC3 | |
| SCHEMBL11528403 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTF2RCLCN2 | |
| SCHEMBL27798143 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HTTCLCN2MIFKMT2A | |
| SCHEMBL11207349 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HTTCLCN2MIFKMT2A | |
| SCHEMBL27351517 | 0.77 | HPGD (0.53) | ALDH1A1LMNAHTTF2RTSHR | |
| Hydrochloric Acid SCHEMBL6379952 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTF2RCLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165068-A1 | Compounds, in particularly of urea derivatives or esters of haloacetamidobenzoic acid and use thereof for the treatment of parasitic diseases | LEPAPE PATRICE (FR) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165068-A1 | Compounds, in particularly of urea derivatives or esters of haloacetamidobenzoic acid and use thereof for the treatment of parasitic diseases | TBCA, GBA1, SLC14A1 | ALDH1A1 157/4885LMNA 2613/4885HTT 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.