SCHEMBL27900520

SCHEMBL27900520

Brc1c(-c2ccccc2)csc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
MAPK1 P28482 2/20 0.43
BACE1 P56817 2/20 0.41
CYP2A6 P11509 1/20 0.38
CYP2B6 P20813 1/20 0.38
DAPK3 O43293 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
LCK P06239 1/20 0.36
CSF1R P07333 1/20 0.36
RET P07949 1/20 0.36
MET P08581 1/20 0.36
PDGFRB P09619 1/20 0.36
FGFR1 P11362 1/20 0.36
PDGFRA P16234 1/20 0.36
PRKACA P17612 1/20 0.36
FLT1 P17948 1/20 0.36
LTK P29376 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16266879 0.80 ALDH1A1 (0.44) ALDH1A1MAPK1BACE1CYP2A6CYP2B6
SCHEMBL5120680 0.77 ALDH1A1 (0.39) ALDH1A1MAPK1BACE1TDO2SMN1; SMN2
SCHEMBL6036925 0.76 BACE1 (0.41) ALDH1A1BACE1CYP2A6CYP2B6DAPK3
Phosphine SCHEMBL28718427 0.74 BACE1 (0.41) ALDH1A1BACE1CYP2A6CYP2B6DAPK3
SCHEMBL12912887 0.72 BACE1 (0.40) ALDH1A1MAPK1BACE1CYP2A6CYP2B6
SCHEMBL22299324 0.71 ALDH1A1 (0.39) ALDH1A1MAPK1CYP2A6CYP2B6MAPK14
SCHEMBL5972870 0.70 SREBF2 (0.38) ALDH1A1MAPK1MAPK14SMN1; SMN2LMNA
SCHEMBL9489536 0.70 NPC1 (0.47) ALDH1A1MAPK1CYP2A6CYP2B6SMN1; SMN2
SCHEMBL10568574 0.70 PTGS1 (0.49) ALDH1A1MAPK1BACE1CYP2A6CYP2B6
SCHEMBL3784206 0.69 BACE1 (0.44) ALDH1A1BACE1CYP2A6CYP2B6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397397-B Diaryl and episulfide and selenides and its synthesis and application 华东师范大学 2019-02-01 CN claimed
CN-105820098-B Diaryl sulfide class compound and its synthetic method and application 华东师范大学 2018-08-24 CN claimed
CN-110467536-A Nitrogenous compound, organic electroluminescence device and photoelectric conversion device SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD 2019-11-19 CN disclosed
CN-110183333-A A kind of electroluminescent organic material and the organic electroluminescence device comprising the material 陕西莱特光电材料股份有限公司 2019-08-30 CN disclosed
CN-110183332-A A kind of aromatic derivant comprising polycyoalkane and the organic electroluminescence device comprising the derivative 陕西莱特光电材料股份有限公司 2019-08-30 CN disclosed
CN-110128279-A Electroluminescent organic material and organic electroluminescence device comprising the material 陕西莱特光电材料股份有限公司 2019-08-16 CN disclosed
CN-109912654-A It is a kind of based on dibenzofurans/dibenzothiophene unit aryl phosphine sulphur organic photoelectrical material and the preparation method and application thereof 南京邮电大学 2019-06-21 CN disclosed
CN-106232771-B The new chromophore architectures of lanthanide chelate 雷度米特图尔库公司 2019-04-30 CN disclosed
CN-106946865-B A kind of aromatic amine derivant and its preparation method and application 长春海谱润斯科技有限公司 2019-04-05 CN disclosed
CN-107118111-B A kind of aromatic amine derivant and its preparation method and application 长春海谱润斯科技有限公司 2019-04-05 CN disclosed
CN-109400603-A Compound and its application in organic light emission field 北京鼎材科技有限公司 2019-03-01 CN disclosed
CN-108912048-A A kind of nitogen-contained heterocycle derivant and its organic electroluminescence device 长春海谱润斯科技有限公司 2018-11-30 CN disclosed
CN-108558874-A A kind of aryl amine derivatives and its organic electroluminescence device containing phenanthroline 长春海谱润斯科技有限公司 2018-09-21 CN disclosed
CN-108440531-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-08-24 CN disclosed
CN-105820098-B Diaryl sulfide class compound and its synthetic method and application 华东师范大学 2018-08-24 CN disclosed
CN-108299439-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-07-20 CN disclosed
CN-108285452-A A kind of pyridine derivatives and its application 华中科技大学 2018-07-17 CN disclosed
CN-108191870-A For benzimidazole simultaneously [1,2-A] benzimidizole derivatives of electronic application UDC 爱尔兰有限责任公司 2018-06-22 CN disclosed
CN-103080105-A Nitrogen-bonded 5-membered heterocyclic substituted dibenzofurans and dibenzothiophenes and their use in organic electronics BASF SE 2013-05-01 CN disclosed