Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 5/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 2/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554350 | 0.79 | RAB9A (0.50) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL27883340 | 0.78 | GRM5 (0.38) | — | |
| SCHEMBL27522099 | 0.77 | ALDH1A1 (0.43) | ACACBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL22387976 | 0.75 | HRH4 (0.45) | HTR7IDH1KCNH3ACACBMAPK1 | |
| SCHEMBL15357780 | 0.73 | HRH4 (0.46) | HTR7KCNH3ACACBMAPK14 | |
| SCHEMBL12411105 | 0.72 | HRH4 (0.45) | HTR7IDH1KCNH3ACACBMAPK14 | |
| SCHEMBL28757676 | 0.72 | KCNH3 (0.42) | KCNH3MAPK14 | |
| SCHEMBL22388247 | 0.70 | HRH4 (0.44) | HTR7ACACB | |
| SCHEMBL709768 | 0.70 | CES1 (0.43) | IDH1KCNH3MAPK14MAPK1 | |
| SCHEMBL27989070 | 0.69 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834387-A | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | BAYER CROPSCIENCE AG | 2012-12-19 | — | — | CN | disclosed |