SCHEMBL27901014

SCHEMBL27901014

CCO[Si](OCC)(OCCCN)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 1/20 0.34
ESR1 P03372 1/20 0.34
CYP19A1 P11511 1/20 0.34
ESR2 Q92731 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
MAOA P21397 1/20 0.33
HRH1 P35367 2/20 0.32
HTR2A P28223 1/20 0.32
RPS6KA5 O75582 1/20 0.32
AKT1 P31749 1/20 0.32
RPS6KA1 Q15418 1/20 0.32
KIF11 P52732 3/20 0.32
KCNH2 Q12809 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
TRPM2 O94759 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662102 0.95 MAOA (0.36) TAAR1MAOAL3MBTL1
SCHEMBL61765 0.90 HTR1B (0.34) HTR1BESR1CYP19A1ESR2TAAR1
SCHEMBL62858 0.89 TAAR1 (0.39) ESR1CYP19A1ESR2TAAR1KIF11
SCHEMBL5619643 0.86 ALDH1A1 (0.42) ESR1ESR2ALDH1A1CYP1A2MAPK1
SCHEMBL3713762 0.86 LTA4H (0.43) CYP19A1L3MBTL1MEN1ALDH1A1CYP1A2
Propylamine SCHEMBL28055720 0.85 ALDH1A1 (0.33) TAAR1HRH1HTR2AKIF11KDM4E
SCHEMBL6697537 0.85 LTA4H (0.41) MAOACYP1A2
SCHEMBL20503699 0.85 ALDH1A1 (0.47) ESR1ESR2ALDH1A1
SCHEMBL14829369 0.84 HTR1B (0.35) HTR1BESR1CYP19A1ESR2TAAR1
SCHEMBL27943310 0.84 LTA4H (0.43) ESR1MAOAHRH1HTR2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110204900-A A kind of flame retardant organoplysiloxane composition and preparation method thereof 广州慧谷化学有限公司 2019-09-06 CN claimed
CN-107760036-A A kind of organic-silicon-modified coating glue and preparation method thereof 东莞兆舜有机硅科技股份有限公司 2018-03-06 CN claimed
CN-110204900-A A kind of flame retardant organoplysiloxane composition and preparation method thereof 广州慧谷化学有限公司 2019-09-06 CN disclosed
CN-107760036-A A kind of organic-silicon-modified coating glue and preparation method thereof 东莞兆舜有机硅科技股份有限公司 2018-03-06 CN disclosed
CN-102832326-A Encapsulating sheet and optical semiconductor element device NITTO DENKO CORP 2012-12-19 CN disclosed