Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23954439 | 0.85 | LMNA (0.44) | LMNAKDM4EMAPTTSHRGMNN | |
| SCHEMBL27941035 | 0.83 | TOP2A (0.40) | LMNACCR1CCR5CCR8MMP2 | |
| SCHEMBL30596581 | 0.81 | CCR1 (0.50) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL21308996 | 0.81 | CCR1 (0.50) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL30447151 | 0.81 | ALDH1A1 (0.47) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL16427120 | 0.80 | CCR1 (0.61) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL28217837 | 0.80 | KDM4E (0.44) | LMNACCR1CCR5CCR8KDM4E | |
| Hydrochloric Acid SCHEMBL5050003 | 0.79 | LMNA (0.46) | LMNAKDM4EMAPTHSP90AA1CYP3A4 | |
| SCHEMBL20208381 | 0.79 | LMNA (0.47) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL20208357 | 0.78 | CCR1 (0.50) | LMNACCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838598-A | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LAB | 2012-12-26 | — | — | CN | disclosed |
| CN-101121715-B | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LAB | 2012-11-14 | — | — | CN | disclosed |