Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901048 | 0.80 | LMNA (0.50) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL30447151 | 0.79 | ALDH1A1 (0.47) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL21308996 | 0.77 | CCR1 (0.50) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL30596581 | 0.77 | CCR1 (0.50) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL9558125 | 0.76 | KDM4E (0.47) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL16427120 | 0.75 | CCR1 (0.61) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL20208381 | 0.74 | LMNA (0.47) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL20208357 | 0.74 | CCR1 (0.50) | KDM4EMAPTLMNAMMP2CCR1 | |
| Phenanthroline SCHEMBL9275301 | 0.73 | LMNA (0.76) | KDM4EMAPTLMNAMMP2CCR1 | |
| SCHEMBL23239898 | 0.72 | KDM4E (0.48) | KDM4EMAPTLMNAMMP2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646367-B | Bipolar compound derived from cis-stilbene/fluorene spirochete | 彩丰精技股份有限公司 | 2018-05-22 | — | — | CN | disclosed |